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Anti-American protests in the Middle East and North Africa this week are prompting cruise lines to re-route ships from the region.

Holland America's Veendam docking at Port of Vancouver's Canada Place @ 7 am after an Alaska cruise

Holland America and Royal Caribbean re-routed ships following news of protests in the region. Photo by Dave Conner.

Holland America says the 1,258-passenger Ryndam will skip a call in La Goulette, Tunisia today and instead visit the Italian island of Sardinia.

Also steering clear of the region is Royal Caribbean, which is dropping a Tuesday call in Alexandria, Egypt scheduled for the 3,114-passenger Mariner of the Seas.